Egg donation procedure



Approximately 40 percent of women no older than 23-25 years old who opt for IVF have chances for a successful pregnancy on their first attempt, while only 12 percent of women aged 40 demonstrate positive results when trying to conceive a child for the first time. Consequently, the use of donor eggs will increase the chance for success rates with IVF, especially if the donor egg is retrieved from a young healthy woman who has undergone screening and has taken all necessary medical tests.

 

Using such a donor material will offer multiple benefits for a woman who experiences some health problems compared to the retrieval of her own eggs.

 

The use of a donor egg is recommended in cases when:

 
  • A woman is no longer capable of producing her own eggs, or they are marked by low reproductive potential resulting from such conditions as premature ovarian failure and ovary resection or removal surgeries.
  • A woman is above 40 (as a woman ages, the quality of her eggs drops off steeply).
  • There is a history of failure with IVF cycles or ovulation induction treatment.
  • A woman is at high risk of recurrent pregnancy loss.
  • A woman is carrying transmittable genetic abnormalities, which poses a threat to her future childrenwho could be affected by hereditary diseases.
 

Egg donor requirements:

 
  • Any woman aged from 20 to 35 is eligible for egg donation if she is in good physical and psychological state and expresses a willingness to become an egg donor.
  • It is obligatory for a woman to be a biological mother of at least one healthy child and have no evidence of inherited diseases.
  • A potential donor should not have any distinctive physical peculiarities, which implies that a woman should be of appropriate stature and height, with no excess weight.
 

Screening of an egg donor

 

A healthy egg donor that meets all the criteria concerning her appearance (height, weight, eye and hair color) can be found at one’s own discretion either via Internet or through the medical records system at the fertility clinic where the infertile woman undergoes treatment. All physical characteristics of the candidate included into the egg donor’s application form are as follows: racial background, eye and hair color, complexion, weight, special achievements, interests, etc. Prior to being registered at the medical records system, an egg donor is obliged to undergo three types of medical evaluation.

 

1. A complete medical checkup, including testing for communicable infectious diseases and specific blood values:

 
  1. BLOOD GROUP & RH
  2. BLOOD ,UREA
  3. HIV
  4. CHLAMYDIA (Ig G &IgM)
  5. PLATELET COUNT
  6. PROLACTIN
  7. SGOT / SGPT
  8. E2
  9. THYROID PROFILE
  10. THALASSEMIA SCREEN (Abnormal Haemoglobin Study)
  11. BLOOD SUGAR (FBS /PPBS/RBS)
  12. VDRL
  13. URINE RE
  14. HCV
  15. LH
  16. USG PELVIS (Please note LMP)
  17. CREATININE
  18. GONORRHEA
  19. CMV (IgG&IgM)
  20. HbSAg
  21. AMH
  22. FSH
  23. CBC/ESR
 

2. Psychological evaluation: testing and an interview with a counselor.

 

3. Genetical evaluation: screening for genetic disorders and counseling with a geneticist.

 

A woman is entitled to a status of an egg donor and can be added to the medical records system once the process of screening is over and a healthiness of a woman is confirmed.

 

Confirmation of a donor. Donor’s arrival for participation in the program.

 

After familiarizing yourself with application forms of various candidates, you decide on choosing one of them. As soon as you inform the specialists of IVF-Sunrise about your decision, you will shortly receive confirmation that a given candidate will be able to participate in your IVF program and serve as an egg donor. Typically, in a few days before a donor’s menstrual period, the specialists of IVF-Sunrise make all the arrangements with regard to a flight, meeting, accommodation in Moscow, and admission of an egg donor to the clinic. A donor is to undergo a follow-up screening for sexually transmitted diseases, as well as go through an ultrasound scan.

 

The IVF-Sunrise company takes it upon itself to create comfortable conditions for a donor during her stay for participation in the program. The service includes:Accommodation, board, transfer, and specialized medical consultation. The company will provide an egg donor with everything she needs, including medications. Our specialists always keep in contact with an egg donor to make sure that a patient is following all the instructions concerning the intake of medications. Also, IVF-Sunrise provides future parents with an opportunity to get to know their egg donor in person. As a rule of thumb, many couples actively use such an opportunity and arrive in Moscow for a meeting with a donor while she undergoes ovulation induction treatment.

 

Stages of IVF cycle with donor eggs. Timing.

 
Ovulation induction in a donor
 

Since a mature ovarian follicle is able to discharge only one egg at a cycle, it is of curtail importance for a donor to take a course of ovulation induction treatment whereby a woman is prescribed hormone-containing medications. These medications trigger the growth of multiple follicles at a time which allows obtaining several embryos at the end of fertilization cycle, thus increasing the success rate. The induction generally starts on the third day of a donor’s cycle and lasts for 10-14 days. As a result, the growth and development of multiple eggs occur. The maturation of follicles is monitored by our specialists via ultrasound exam.

 
Ovarian follicle puncture for egg retrieval in a donor
 

The procedure is performed through vagina under ultrasound guidance and anesthesia and lasts for about 10 minutes after which a donor may take a rest for several hours in the fertility clinic.

 
Assisted reproduction
 

After the egg retrieval procedure, the fertility physician may start a fertilization process with the use of either partner’s or donor sperm. Sperm can be collected on the same day the ovarian follicle puncture is performed and can be stored in a frozen condition up to the beginning of fertilization stage. Once the sperm penetrates the egg, the embryos begin to develop which takes five days. After making sure that the embryo is viable, the embryologist may start the procedure of embryo transfer to the uterus of a patient or surrogate mother. Afterwards, the high-quality embryos are frozen for use in later treatment cycles in case of pregnancy failure or if a patient is planning to conceive another child in the future. Overall, if the donor feels good, in two or three days after ovarian follicle puncture she may return home with a financial compensation for delivering eggs.

 

Timing

 

The time when the egg and embryo may be collected will depend on the time needed for donor selection. Typically, once a donor is confirmed, the whole IVF cycle with donor oocytes – from the donor’s arrival and admission to the hospital and up to the end of embryologic stage – continues for about 3 weeks.